The New Zealand Institute for Public Health and Forensic Science (PHF Science) was formerly named The Institute of Environmental Science and Research (ESR).

Urate-induced epigenetic modifications in myeloid cells

Abstract

Hyperuricemia is a metabolic condition central to gout pathogenesis. Urate exposure primes human monocytes towards a higher capacity to produce and release IL-1β. In this study, we assessed the epigenetic processes associated to urate-mediated hyper-responsiveness.

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