The Institute of Environmental Science and Research (ESR) has changed its name to the New Zealand Institute for Public Health and Forensic Science (PHF Science) as of 1 July 2025. The website address is now www.phfscience.nz. Visitors are automatically redirected to the new address. Please check and update any links and bookmarks.

Establishing the limit of detection of massively parallel sequencing using laser micro-dissected cells

Abstract

Massively parallel sequencing is fast emerging as an increasingly useful tool for forensic science. As part of our ongoing validation of this technology we wanted to both ensure compatibility of the technology with laser microdissected (LMD) cells and use the LMD to explore the minimal and optimal numbers of cells required to generate informative profiles.

view journal