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Clopidol: Residue

Please note: As of 1 July 2025, the New Zealand Institute for Public Health and Forensic Science (PHF Science) is the new name for the Institute of Environmental Science and Research (ESR). Research and reports published prior to this date may reference the organisation’s former name.

Abstract

Clopidol is a pyridone-derivative structurally related to the quinolones. Pyridones are the carbonyl tautomeric forms of hydroxypyridines. The tautomeric equilibrium of 3,5-dichloro-2,6-dimethyl-1H- pyridin-4-one and 3,5-dichloro-2,6-dimethyl-1H-pyridin-4-ol is a common phenomenon with aromatic compounds (Monastyrskyi, Kyle and Manetsch, 2014).

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